What must be done before using human-derived biological materials in research?

Obtaining informed consent from donors is an essential ethical requirement before using human-derived biological materials in research. This process ensures that individuals are fully aware of how their biological samples will be used, including the potential risks and benefits, thereby respecting their autonomy and rights. Informed consent is not just a legal requirement; it is a foundational principle in bioethics that protects participants from potential exploitation and ensures that they are willingly participating in research.

By securing informed consent, researchers can demonstrate their commitment to ethical standards and the responsible conduct of research. This practice helps to foster trust between researchers and participants, which is crucial in any scientific endeavor involving human subjects. It also ensures compliance with regulatory guidelines surrounding human research ethics, which require transparency and respect for individual rights.

The other choices might involve steps that could be necessary in the research process, but they do not address the ethical imperative of ensuring that donors have given their explicit permission for their biological materials to be used in research.